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Table 3 Breed-specific over-represented human-derived phenotypes as defined in the human GWAS catalogue

From: Whole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systems

BreedHuman phenotypeAdjusted p-valueOverlapping genes
Black SlavonianRed vs brown/black hair colour3.37 × 10−20MC1R, TCF25, CHMP1A, FANCA, SPIRE2, CDK10, DPEP1, DEF8, CBFA2T3
Black SlavonianLow tan response1.06 × 10−11DBNDD1, MC1R, CHMP1A, FANCA, SPIRE2, DEF8
Black SlavonianBrown vs black hair colour2.81 × 10−06MC1R, TCF25, CDK10, DEF8
Black SlavonianBlond vs brown/black hair colour1.49 × 10−04DBNDD1, MC1R, TCF25, CDK10, SPATA2L
Cinta SeneseBlood protein levels2.63 × 10−02EDAR, GZMM, PRSS57, PRTN3, AZU1, ELANE
GasconRed vs brown/black hair colour1.83 × 10−09TCF25, FANCA, SPIRE2, CBFA2T3
KrškopoljeHeight8.46 × 10−05LYN, MOS, MC4R, SDR16C5, PLAG1, PENK, CHCHD7, RPS20
KrškopoljeHeel bone mineral density4.35 × 10−02MC4R, PLAG1, ACYP2, SPTBN1
Italian LandraceHeight6.91 × 10−05LYN, MOS, PLAG1, CHCHD7, NCAPG, RPS20, LCORL
Italian Large WhiteHeight3.50 × 10−04LYN, MOS, SDR16C5, GNPTAB, PLAG1, PENK, CHCHD7, RPS20
MoravkaBlood protein levels1.89 × 10−02PRTN3, NRTN, AZU1, CD36, ELANE
SardaHeight2.43 × 10−03LYN, MOS, PLAG1, CHCHD7, RPS20, SERPINI1