Cross-species inference of long non-coding RNAs greatly expands the ruminant transcriptome

Table 2 Direct mapping of lncRNA transcripts to the genome of another species

Species 1 (in which lncRNAs are captured by RNA-seq libraries)	Species 2 (in which lncRNA can be inferred)	Number of lncRNA models detected within a region of conserved synteny between species 1 and 2, but not captured by the RNA-seq libraries of species 2	Number of lncRNA models from species 1 mapped to the genome of species 2	% of lncRNA models detected by direct genome mapping	Number of intergenic regions in the syntenic blocks conserved between these two species	% of intergenic regions in which a lncRNA from species 1 is inferred in species 2
Cattle	Goat	2593	1213	46.78	5964	20.34
	Human	163	20	12.27	886	2.26
	Sheep	2939	1219	41.48	5854	20.82
Goat	Cattle	2593	286	11.03	5964	4.8
	Human	76	9	11.84	1054	0.85
	Sheep	991	164	16.55	4076	4.02
Human	Cattle	163	16	9.82	886	1.81
	Goat	76	15	19.74	1054	1.42
	Sheep	93	18	19.35	760	2.37
Sheep	Cattle	2939	775	26.37	5854	13.24
	Goat	991	507	51.16	4076	12.44
	Human	93	15	16.13	760	1.97

The results show that lncRNA transcripts assembled using the RNA-seq libraries of only one species can in many cases be directly mapped to the genome of another species, assuming the lncRNA is located within a region of conserved synteny

ISSN: 1297-9686